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Wild Jujube Extract (Jujuboside) | Natural Sleep Aid & Anti-Anxiety Ingredient Supplier
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Certificates
+ISO9001; HACCP -
Product Specification
+2% Jujuboside -
Factory Environment
+CGMP Factory
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Product Advantages
+Batch Ready Stock; Raw Material guarantee; ＜50ppm（Compliant with USP/EP standards） -
Product Evaluation
+Testing Report; Meet EU Grade -
Product Deliveries
+DHL, Fedex, UPS, EMS, as request
What is Ashwagandha Extract?
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Product Name: |
Wild Jujube Extract |
Latin Name: |
Ziziphi Spinosae Semen |
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Specification: |
2% Jujuboside |
Appearance: |
Brown Color |
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Test Method: |
UV |
Brand: |
Risun |
Wild Jujube extract is an aggregate of active ingredients isolated from the dried mature seeds of the Rhamnoaceae plant Jujube by physical or chemical means. The preparation process includes key steps such as frying, crushing, reflux extraction, and freeze-drying, among which the frying process significantly increases the content of hepatoprotective components such as spinosin and jujube saponin A/B
Ziziphus jujuba Extract | Neuromodulation and sleep optimization solutions
Innovative extraction process
Production technology:
Macroporous resin purification: Jujuboside A+B content ≥2% (UV detection)
Nano-encapsulation technology: Blood-brain barrier penetration rate increased by 3.5 times
Quality control system:
Heavy metal detection (arsenic <0.2ppm, cadmium not detected)
ISO9001&HACCP; HALAL
Pesticide residues (366 screening items not detected)
Jujubosides | Multi-target mechanism of action
Core active ingredients:
Jujuboside A
Jujuboside B
Neuromodulation pathways:
GABA_A receptor regulation: Enhanced chloride influx (EC50=3.2μM)
5-HT1A receptor activation: 42% increase in 5-HT levels in the hippocampus
HPA axis regulation: Normalization of cortisol circadian rhythm
Neuroprotection: Inhibition of Aβ25-35 toxicity (neuronal survival rate +68%)
Clinical evidence of efficacyies
Improved sleep quality
Insomnia patients (4-week trial): 52% reduction in sleep time
Sleep efficiency: Increased from 78% to 89% (Actigraphy data)
Anxiety relief
GAD-7 scale score decreased by 44% (n=120, 8-week intervention)
Salivary amylase activity decreased by 31% (stress biomarker)
Cognitive function protection
Patients with mild cognitive impairment: MMSE score improved by 2.8 points (6 months)
Long-term memory retention rate: Morris water maze test increased by 35%
Cardiovascular protection
Heart rate variability (HRV): LF/HF ratio improved by 28%
Hypertension assistance: 12mmHg reduction in systolic blood pressure (day and night monitoring)
Technical parameters
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Item |
Specification |
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Apperaance |
Brown-yellow fine powder |
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Active ingredients |
Total Jujuboside ≥2%（UV） |
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Recommended dosage |
200-600mg/day(1 hour before bedtime) |
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Stability |
24 months (aluminum foil bag filled with nitrogen) |
Application scenarios and formula solutions
Sleep health products
Quick-acting sleep gummies: 300mg extract + 0.3mg melatonin (onset time shortened to 20 minutes)
Circadian rhythm regulation capsules: 100mg in the morning (regulates cortisol) + 400mg in the evening (promotes sleep)
Emotional management
Anti-anxiety spray: 5% jujube seed saponin (absorbed by sublingual mucosa, takes effect in 5 minutes)
CBD synergistic formula: 200mg jujube seed extract + 15mg broad-spectrum CBD (Entourage effect)
Brain health support
Neuroprotective powder: 500mg + Phosphatidylserine (PS) (improves REM sleep ratio)
Cognitive enhancement tablets: 1:1 compound with Bacopa monnieri extract (increases BDNF levels)
Cardiovascular health
Nighttime blood pressure management: sustained-release tablets (continuous release for 8 hours)
HRV optimization capsules: synergistic formula with rosmarinic acid
Usage specifications and contraindications
Recommended dose
General sleep aid: 300-400mg/day (1 hour before bedtime)
Severe insomnia: Can be increased to 600mg/day (no more than 8 weeks)
Daytime anti-anxiety: 100-200mg/time (twice a day)
⛔ Precautions
Combined with sedatives: requires doctor's guidance (may enhance CNS depression)
Two weeks before surgery: recommended to stop (potential anticoagulant effect)
Pregnancy: lack of safety data
FAQ
Q: What is the difference between jujube saponin and melatonin?
A: Ziziphus jujuba seeds achieve physiological sleep through multi-target regulation (GABA+5-HT), without the risk of circadian rhythm interference of melatonin, and are more suitable for long-term use.
Q: How long does it take for the best onset of action?
A: Clinical data show that continuous use for 3-5 days will be effective (improvement of sleep latency), and continuous use for 2 weeks will have significant effects (improvement of sleep efficiency).
Q: Is it suitable for menopausal insomnia?
A: Our clinical trials included a group of women aged 45-55, and the number of hot flash-related awakenings was reduced by 47% (synergistic effect with black cohosh extract).
