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Nattokinase Spurs Global Thrombosis Prevention Shift: Chinese Pioneer Taps Decade-Led Expertise

2025-03-20

As China's earliest company specializing in the research, development, and export of nattokinase, Risun Bio-Tech Inc has leveraged over a decade of technological expertise and global market experience to advance the scientific application and internationalization of this natural thrombolytic ingredient. Derived from traditional Japanese fermented food natto, nattokinase is globally recognized for its unique fibrinolytic activity, validated by clinical studies to enhance blood circulation and prevent thrombus formation, positioning it as a key ingredient in cardiovascular health.
In the European and American dietary supplement markets, one out of every three cardiovascular health products contains nattokinase. As China's first national high-tech enterprise to achieve full industrial chain independence for nattokinase, Risun Biotechnology has written oriental wisdom in the global thrombosis prevention track with more than 1 core patents and a 92% international customer repurchase rate. This company, founded in the heart of the Qinling Mountains in 2014, is reshaping the modern life science value of millennium fermented foods with millimeter-level precision control of microbial fermentation engineering.
With a focus on professionalism, Risun collaborates with global research institutions to decode nattokinase's mechanisms, employing innovations like enzyme activity stabilization technology and high-purity Extraction processes to meet international pharmacopeia standards. The company holds ISO, HACCP, and other certifications, supplying premium nattokinase raw materials to medical institutions and health brands across 30+ countries in Europe, America, Southeast Asia, and beyond.
20,000 FU/g activity standard: using biphasic microcapsule embedding technology, the activity retention rate is ≥95% after 18 months of storage at room temperature (the industry average is 72%) 
Purity revolution: through molecular imprinting chromatography, the impurity protein content is controlled below 0.8%, which meets the USP40-NF35 injection grade standard 
Intelligent fermentation: 500m³ fully automatic fermentation tank group equipped with AI metabolic control system, the unit output is increased to 18g/L (reaching the international leading level)
Industry experts emphasize that Nattokinase Production demands rigorous technical expertise. Risun's in-house biotech fermentation center and quality control laboratory ensure end-to-end precision from strain selection to final product delivery, achieving a stable activity level exceeding 20,000 FU/g—far above industry benchmarks. Moving forward, the company will deepen industry-academia partnerships to expand nattokinase's applications in functional foods and pharmaceuticals, delivering safer thrombosis solutions worldwide.