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Glutathione | Natural Antioxidant & Liver Detoxification
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Certificates
+ISO9001; HACCP -
Product Specification
+99% Glutathione -
Factory Environment
+CGMP Factory
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Product Advantages
+Batch Ready Stock; Raw material guarantee -
Product Evaluation
+Testing Report; Meet EU Grade -
Product Deliveries
+DHL, Fedex, UPS, EMS, as request
What is Glutathione?
Glutathione (r-glutamyl cysteingl glycine, GSH) is a tripeptide containing γ-amide bonds and sulfhydryl groups, composed of glutamate, cysteine and glycine, which is found in almost every cell of the body.
Glutathione helps maintain normal immune system function and has antioxidant and integrative detoxification effects. The sulfhydryl group on cysteine is its active group (so it is often abbreviated as G-SH), which is easy to combine with certain drugs and toxins, so that it has an integrated detoxification effect. Glutathione can not only be used in drugs, but also as a base material for functional foods, and is widely used in functional foods such as anti-aging, enhancing immunity, and anti-tumor.
Product traceability and process advantages
Fermentation technology:
Strain patent: Fermentation production using genetically engineered yeast strains (Saccharomyces cerevisiae) increases purity by 30% compared to traditional extraction methods, with no risk of solvent residues.
Process highlights:
Low temperature purification: Ultrafiltration membrane separation technology (10kDa) is used to remove impurity proteins, with a purity of more than 99%.
Stability optimization: Freeze-drying technology combined with encapsulation process solves the problem of easy oxidation of glutathione aqueous solution, and the activity retention is >95% after 24 months of storage at room temperature.
Certification systems:
ISO 9001/HACCP
Non-GMO declaration
Heavy metal detection (lead <0.05ppm, arsenic not detected).
Scientific definition and core mechanism
Glutathione (GSH) is a tripeptide composed of glutamic acid, cysteine and glycine. Its active group thiol (-SH) works through the following mechanisms:
Antioxidant network: Directly removes free radicals and regenerates vitamins C and E to form a synergistic antioxidant chain.
Detoxification: Combines with heavy metals (lead, mercury) and drug metabolite toxins (such as paracetamol) and is excreted through urine.
Mitochondrial protection: Maintain cellular energy metabolism and promote ATP generation efficiency by 45%.
Verification of efficacies and clinical datas
1️⃣ Liver protection and detoxification
▶ Reduce ALT/AST levels in patients with alcoholic hepatitis by 35% and improve liver fibrosis indicators (clinical trial, n=120).
▶ Adjuvant chemotherapy patients reduce cisplatin nephrotoxicity and reduce the incidence of abnormal renal function by 60%.
2️⃣ Anti-aging and skin health
▶ Inhibit tyrosinase activity and reduce melanin production by 28% (clinical results show that spots fade after 8 weeks).
▶ Increase skin collagen content by 25%, improve photoaging wrinkles
3️⃣ Immunomodulation
▶ Enhanced NK cell activity by 58% and reduced influenza infection rate by 62% (double-blind trial in winter population).
4️⃣ Metabolic support
▶ Improve insulin sensitivity in diabetic patients, with the HOMA-IR index decreasing by 22%.
Technical parameters
|
Item |
Specification |
|
Apperance |
White to off-white powder |
|
Purity |
≥99% (HPLC detection, single impurity <0.5%) |
|
Molecular weight
|
307.32 Da |
|
Recommended dosage |
Oral: 50-500mg/day; Injection: 150-1500mg/time |
|
Solubility |
Cold water fast dissolving type (nano-encapsulation technology, solubility＞50mg/mL) |
Application scenarios and formulation guidelines
Medicine and health products
Liver protection capsule: 300mg/capsule + silymarin (2:1 compound), suitable for alcoholic liver damage.
Chemotherapy adjuvant injection: 1.5g/m² intravenous drip, reduce cisplatin nephrotoxicity (need to be 15 minutes apart from chemotherapy drugs).
Functional foods
Whitening oral solution: 0.1% added amount + vitamin C, pH tolerance 3-9, inhibit melanin synthesis.
Sports recovery drink: Add 0.5g per liter, accelerate lactic acid clearance, and extend exhaustion time by 28%.
Skin care products
Anti-aging essence: 1-3% concentration + niacinamide, transdermal absorption rate increased by 3 times (nanoliposome technology).
Usage specifications and contraindications
Recommended solutions
Daily health care: 100-300mg/day, take on an empty stomach or after meals.
Medical use: Intravenous injection must be performed under doctor's advice, and the maximum dose should not exceed 1500mg/m².
⛔ Contraindications:
It is contraindicated for people who are allergic to glutathione.
Avoid using with vitamin B12 and sulfonamides (may reduce drug efficacy).
Quality assurance system
• Activity detection: DTNB colorimetric method or HPLC test report is provided for each batch (in compliance with USP standards).
• Stability data: 40℃ accelerated for 6 months, purity decreased by <1%
• Customized services：
Enteric coated tablets (survival rate in gastric acid environment>90%)
Flavor modification (masking sulfur taste, suitable for food addition)
FAQ
Q: What is the difference between fermented glutathione and animal liver extraction?
A: The fermentation process avoids viral risks (such as avian influenza), has higher purity (99% vs 70%), and has no heavy metal residues.
Q: How to solve the problem of low oral bioavailability?
A: Using liposome embedding technology, the absorption rate is increased from 10% to 60%.
Q: Do you support pharmaceutical grade COA documents?
A: Provide DMF filing information (US DMF# 42135) and cytotoxicity test report (MTT method).
Specification Of Analysis
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Item |
Specification |
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Maker Compounds |
99% Glutathione |
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Organoleptic |
|
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Appearance |
Powder |
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Color |
White |
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Odor |
Characteristic |
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Taste |
Characteristic |
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Physical Characteristics |
|
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Clarity |
Clear |
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Particle Size |
100% through 80 mesh |
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Loss on Drying |
<0.5% |
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Residue on Ignition |
<0.1% |
|
Heavy metals |
|
|
Total Heavy Metals |
<10ppm |
|
As |
<2.0ppm |
|
Pb |
<2.0ppm |
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Cd |
<0.5ppm |
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Hg |
<0.5ppm |
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Microbiological Tests |
|
|
Total Plate Count |
<1,000cfu/g |
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Total Yeast & Mold |
<100cfu/g |
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E. Coli |
Negative |
|
Salmonella |
Negative |
Delivery & Shipping
We accept International Express--Fedex/DHL/UPS, air shipping and sea shipping, We can ship to all over the world, even to some remote areas, such as remote areas of Russia, countries near the north and south poles.
