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Ganoderma Lucidum Extract (Ganoderma Lucidum polysaccharide) | Expert in Immune Regulation & Anti-Tumor Auxiliary Raw Materials
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Certificates
+ISO9001; HACCP -
Product Specification
+50% Polysaccharide -
Factory Environment
+CGMP Factory
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Product Advantages
+Batch Ready Stock; Raw Material guarantee; ＜50ppm（Compliant with USP/EP standards） -
Product Evaluation
+Testing Report; Meet EU Grade -
Product Deliveries
+DHL, Fedex, UPS, EMS, as request
What is Ganoderma Lucidum Extract?
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Product Name: |
Ganoderma Lucidum Extract |
Latin Name: |
Ganoderma lucidum (Curtis) P. Karst. |
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Specification: |
50% Polysaccharide
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Appearance: |
Brown to Yellow Brown Color |
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Test Method: |
UV |
Brand: |
Risun |
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Storage Condition: |
Sealed and light-proof, cool and dry (shelf life 24 months) |
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Ganderma Lucidum Extract, derived from Ganoderma lucidum, contains polysaccharides, triterpenes, and peptides. It boosts immunity, fights oxidation, and may inhibit tumors. Used for anti-aging, liver protection, and cardiovascular health. Available as capsules or liquids. Generally safe but consult a doctor if taking blood thinners. 100 words.
Ganoderma lucidum extract (Ganoderma lucidum Extract) | Immune network regulation system
Innovative extraction process
Triple biotechnology refining:
Low-temperature enzymatic cell wall breaking: Polysaccharide yield increased by 60% (compared with traditional hot water extraction)
Molecular weight classification technology: 10-50kDa active fragment enrichment (tumor inhibition rate ↑35%)
Protein removal purification: Protein residue <0.5% (suitable for injection-grade applications)
Ganoderma polysaccharides (Ganoderma Polysaccharides) | Core active ingredients
Key bioactive components:
β-(1→3)-D-glucan (main chain)
β-(1→6)-D-glucan (side chain)
Proteoglycan complex (FIP-glu)
Multi-target immune regulation mechanism:
Innate immune activation
Binding to Dectin-1 receptor (macrophage activity ↑80%)
Promoting TNF-α secretion (ELISPOT detection +5 times)
Adaptive immune regulation
Increasing IgA secretion (intestinal lymphoid tissue +45%)
Regulating Th1/Th2 balance (optimizing IFN-γ/IL-4 ratio)
Tumor microenvironment intervention
Inhibiting PD-L1 expression (T cell killing efficiency ↑62%)
Reducing M DSCs (myeloid suppressor cells↓55%)
Clinical evidence of efficacyies
Immunoenhancement
Postoperative infection rate: Decreased by 73% (colorectal cancer patients, n=180)
Influenza antibody titer: Increased by 2.8 times in the vaccine-assisted group
Tumor assistance
Chemotherapy tolerance: White blood cell count maintained>3.5×10⁹/L (85% of patients)
Progression-free survival: Extended by 4.3 months (Phase III NSCLC study)
Metabolic regulation
Fasting blood glucose: decreased by 2.1mmol/L (diabetic mouse model)
Gut flora: Bifidobacterium abundance increased by 3 times
Radioprotection
Myelosuppression: platelet recovery accelerated by 5 days after radiation
DNA repair: γ-H2AX foci reduced by 68%
Technical parameters
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Item |
Specification |
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Appearance |
Off-white to light yellow powder |
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Active ingredients |
Polysaccharide≥50% |
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Solubility |
Soluble in hot water (completely dissolved above 80°C) |
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Recommended dosage |
Oral: 200-1000mg/day |
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Injection: 5-20mg/kg (medical monitoring) |
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Stability |
24 months (moisture-proof and light-proof) |
Application scenarios and formula guidelines
Immune health products
Postoperative recovery granules: 500mg polysaccharide + glutamine (twice a day)
Children's immune soft candy: 100mg low molecular weight fragments (palatability optimization)
Tumor adjuvant
Chemotherapy combined with infusion: 10mg/kg polysaccharide (relieve bone marrow suppression)
Targeted drug enhancer: Nanoliposome encapsulation (tumor targeted accumulation)
Metabolic management
Blood sugar balance capsule: compounded with mulberry leaf extract (α-glucosidase inhibition)
Intestinal bacteria regulating powder: Prebiotic compatibility (FOS: polysaccharide = 1:2)
Special protection
Nuclear radiation emergency: Fast-dissolving oral preparation (taken within 6 hours after the accident)
Astronaut protection: Space environment immune maintenance system
Use specifications and contraindications
Recommended dose
Daily immune support: 300-500mg/day (30 minutes before meals)
Radiotherapy and chemotherapy adjuvant: 800-1000mg/day (taken in 3 times)
Acute phase intervention: Injections require strict medical supervision
⛔ Precautions
Autoimmune diseases: Use with caution during active phase (need guidance from an immunologist)
Organ transplant recipients: Prohibited (may weaken the effect of immunosuppressants)
Allergic constitution: Skin test required for first use (especially injectable formulations)
FAQ
Q: What is the difference between Ganoderma lucidum polysaccharide and Lentinan?
A: Ganoderma lucidum polysaccharide contains a unique triple helix structure (3 times stronger anti-tumor activity) and has better Th1 polarization ability (2.4 times more IFN-γ induction).
Q: How does molecular weight affect efficacy?
A: 10-50kDa fragments are most suitable for immune activation (macrophage uptake rate 85%), <10kDa fragments focus on intestinal regulation, and we provide molecular weight customization services.
Q: Can it be used in combination with PD-1 inhibitors?
A: Preclinical studies have shown synergistic effects (tumor-infiltrating CD8+T cells increased 3 times), but administration needs to be separated by 2 hours to avoid direct interactions.
