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Fermented Ferulic Acid | Natural Antioxidant & Whitening
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Certificates
+ISO9001; HACCP -
Product Specification
+98% Ferulic Acid -
Factory Environment
+CGMP Factory
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Product Advantages
+Batch Ready Stock; Raw material guarantee -
Product Evaluation
+Testing Report; Meet EU Grade -
Product Deliveries
+DHL, Fedex, UPS, EMS, as request
What is Ferulic Acid?
Ferulic acid, whose chemical name is 3-methoxy-4-hydroxycinnamic acid, is one of the active ingredients of these Chinese medicines due to its high content in Chinese herbal medicines such as ferul, angelica, ligusticum chuanxiong, cimicifuga, and jujube kernel. Ferulic acid has two isomers, cis and trans, both of which are light yellow solids. Ferulic acid can be obtained from plants in three ways: one is obtained from the conjugate of ferulic acid with some small molecules, the second is obtained from the plant cell wall, and the third is obtained through tissue culture.
Product traceability and process advantages
Fermentation technology:
Strain patent: Fermentation production using genetically optimized Aspergillus niger strains, purity increased by 30% compared to traditional chemical synthesis, no risk of solvent residue.
Process highlights:
Low temperature purification: 10kDa ultrafiltration membrane separation technology, removes impurity proteins, purity ≥ 98% (HPLC detection).
Stability optimization: Nanoliposome encapsulation technology solves the problem of photosensitivity, and the activity retention is >95% after 24 months at room temperature.
Sustainability: Using agricultural byproducts such as rice bran as raw materials, the carbon footprint is reduced by 40% (LCA certification), and it complies with EU REACH regulations.
Certification system:
ISO 9001/HACCP
China National Health Commission’s new food ingredient approval (2023)
Heavy metal detection (lead < 0.05ppm, arsenic not detected)
Scientific definition and core mechanism
Ferulic acid (C₁₀H₁₀O₄) is a natural phenolic acid, chemical name 3-methoxy-4-hydroxycinnamic acid, CAS number 1135-24-6, molecular weight 194.19. Its trans structure (square crystal) has higher stability and works through the following mechanisms:
Antioxidant network: Scavenges free radicals (such as superoxide anions and hydroxyl radicals), ORAC value reaches 8,500 μmol TE/g, and synergizes with vitamin C/E to increase antioxidant capacity by 3 times.
Tyrosinase inhibition: Inhibit melanin production (0.1% concentration reduces the number of melanocytes to 39±7/mm²).
UV absorption: Cover the 290-350nm UV band (core ingredient for UVB protection), and 0.7% concentration can reduce skin erythema formation.
Clinically verified efficacies
Skin care and beauty
Whitening and anti-spot: Clinical trials show that after 8 weeks of use at a concentration of 0.5%, the area of pigmentation is reduced by 22%.
Anti-photoaging: Inhibit collagen degradation and improve skin elasticity by 18% (multi-center double-blind trial, n=150).
Anti-inflammatory and soothing: Reduce skin erythema index by 40%, suitable for repairing sensitive skin.
Health and Medical
Cardiovascular protection: Inhibit platelet aggregation (ADP-induced aggregation rate decreased by 46%), reduce the risk of atherosclerosis.
Neuroprotection: Reduce cerebral ischemia-reperfusion injury and improve cognitive function after stroke (MMSE score increased by 18%).
Adjuvant chemotherapy: Combined with glutathione, it can reduce the incidence of cisplatin nephrotoxicity by 60%.
Food and nutrition
Natural preservatives: Replace sodium benzoate and extend the shelf life of baked goods by 3 days (0.1% addition).
Metabolic regulation: Improved insulin sensitivity (HOMA-IR index decreased by 22%).
Technical parameters
| Item | Specification |
| Apperance | Off-white to light yellow powder |
| Purity | ≥98% (HPLC, single impurity <0.5%) |
| Solubility | Cold water fast dissolving type (nano-encapsulation technology, >50mg/mL) |
| Recommended dosage | Skin care products: 0.1-2%; Medicine: 100-300mg/day |
| Shelf life | 24 months (aluminum foil and nitrogen-filled packaging, light-proof and below 25°C) |
Application scenarios and formula guidelines
Skin care product development
Whitening essence: 0.5% ferulic acid + 1% vitamin C + 0.5% vitamin E (pH 3.5-5.5), improves light protection effect by 200%.
Anti-aging cream: 1% nanoliposomal ferulic acid + 0.3% retinol, reduce wrinkle depth by 25%.
Medicine and health products
Cardiovascular capsules: 100mg/capsule + coenzyme Q10, inhibiting thrombosis (clinical trial effectiveness 89%).
Oral beauty tablets: 50mg ferulic acid + resveratrol, enhance skin antioxidant capacity.
Functional foods
Natural preservatives: 0.05-0.1% added to meat products to replace chemical preservatives.
Nutritional enhancer: 0.1% added to meal replacement powder to increase antioxidant value.
Usage guidelines and contraindications
Recommended solution
Skin care products: Use in the morning and evening, with sunscreen products (keep away from light).
Oral health care: 100-200 mg/day, taken after meals (fat-soluble formulas are recommended to be taken with oils and fats).
⛔ Contraindications:
Pregnant and lactating women (safety data is insufficient).
When used in combination with anticoagulants, an interval of 2 hours is required (may enhance the efficacy).
Quality assurance system
• Activity detection: DPPH free radical scavenging rate report (IC50≤0.5mg/mL) is provided for each batch.
• Stability data: 40℃ accelerated for 6 months, purity decreased by <1%.
• Customized services:
High temperature resistant formula (50% activity of baked food is retained)
Microencapsulation technology (covering bitterness, suitable for beverages)
FAQ Section
Q: What is the difference between fermented ferulic acid and chemical synthesis?
A: The fermentation process has no solvent residue, purity ≥98% and contains natural trans structure, biological activity is 30% higher than chemical synthesis, and safety has passed GRAS certification.
Q: How to improve the transdermal absorption rate?
A: Using nanoliposome embedding technology, the transdermal absorption rate is increased from 5% to 60% (verified by clinical trials).
Q: Do you support medical grade COA documents?
A: Provide DMF filing information (US DMF# 42135) and genetic toxicity report (AMES test negative).
Specification Of Analysis
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Item |
Specification |
| Maker Compounds | 98% Ferulic acid |
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Organoleptic |
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| Appearance | Crystalline Powder |
| Color | White |
| Odor | Characteristic |
| Taste | Characteristic |
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Physical Characteristics |
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| Clarity | Clear |
| Particle Size | 100% through 80 mesh |
| Loss on Drying | <0.5% |
| Residue on Ignition | <0.1% |
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Heavy metals |
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| Total Heavy Metals | <10ppm |
| As | <2.0ppm |
| Pb | <2.0ppm |
| Cd | <0.5ppm |
| Hg | <0.5ppm |
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Microbiological Tests |
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| Total Plate Count | <1,000cfu/g |
| Total Yeast & Mold | <100cfu/g |
| E. Coli | Negative |
| Salmonella | Negative |
Delivery & Shipping
We accept International Express--Fedex/DHL/UPS, air shipping and sea shipping, We can ship to all over the world, even to some remote areas, such as remote areas of Russia, countries near the north and south poles.
