+86 13759939507
Fermented Coenzyme Q10 | Natural antioxidant & Energy Metabolism
-
Certificates
+ISO9001; HACCP -
Product Specification
+98% Coenzyme Q10 -
Factory Environment
+CGMP Factory
-
Product Advantages
+Batch Ready Stock; Raw material guarantee -
Product Evaluation
+Testing Report; Meet EU Grade -
Product Deliveries
+DHL, Fedex, UPS, EMS, as request
What is Coenzyme Q10?
Coenzyme Q10 (CoQ-10) is a vitamin-like substance found throughout the body, especially the heart, liver, kidneys, and pancreas. It is eaten in small quantities in meat and seafood. Coenzyme Q10 can also be manufactured in a laboratory, and it is used as a medicine. Many people use CoQ10 to treat heart and blood vessel disorders, such as congestive heart failure (CHF), chest pain (angina), high blood pressure, and heart problems associated with certain anti-cancer drugs.
Product traceability and process advantages
✅ Fermentation technology:
Strain patent: Fermentation production using Cryptococcus luteolus L3302 optimized by genetic engineering, purity increased by 30% compared with traditional chemical synthesis, no risk of solvent residue
Process highlights:
Low temperature purification: 10kDa ultrafiltration membrane separation technology, remove impurity proteins, purity ≥98% (HPLC detection).
Stability optimization: Nanoemulsion embedding technology (red pine seed oil matrix), bioavailability increased by 4-8 times, activity retention >95% after 24 months at room temperature.
Sustainability: Zero animal-derived ingredients, 40% reduction in carbon footprint (LCA certification), compliant with EU REACH regulations.
✅ Quality certification:
ISO 9001/HACCP certification
China National Health Commission’s new food ingredient approval (2023)
Heavy metal detection (lead < 0.05ppm, arsenic not detected)
Scientific definition and core mechanism
Coenzyme Q10 (C₅₉H₉₀O₄) is a fat-soluble quinone compound, CAS number 303-98-0. As a core component of the mitochondrial electron transport chain, it works through the following mechanisms:
Energy metabolism: Promotes ATP production and improves cell energy efficiency by 45%.
Antioxidant network: Scavenges free radicals, regenerates vitamin E/C, and ORAC value reaches 8,500 μmol TE/g.
Cardioprotection: The highest concentration is in the myocardium, supporting cardiac contractile function (clinically shown to reduce mortality in patients with heart failure).
Verify efficacIES and clinical dataS
1️⃣ Cardiovascular health support
▶ Improve the survival rate of patients with chronic heart failure (Q-SYMBIO trial, n=420, all-cause mortality reduced by 43%).
▶ Reduce systolic blood pressure of hypertensive patients by 10-17 mmHg (dose 100-200 mg/d, for 12 weeks).
2️⃣ Antioxidant and anti-aging
▶Inhibits skin collagen degradation, clinically showing that wrinkle depth is reduced by 22% after 8 weeks.
▶ Improve the efficiency of mitochondrial biosynthesis and delay the accumulation of cell aging markers.
3️⃣ Exercise and metabolic enhancement
▶ Extend exhaustion time by 28%, increase blood lactate clearance by 40% (double-blind test for athletes)
.▶Improve insulin sensitivity, HOMA-IR index decreased by 22% (study of prediabetes population).
4️⃣ Assisted medical applicationS
▶ Relieve the side effects of statins (such as myalgia), the recommended combined dosage is 30-100mg/d.
Technical parameters
|
Item |
Specification |
|
Appearance |
Yellow to orange-yellow crystalline powder |
|
Purity |
≥98% (HPLC detection, single impurity <0.5%) |
|
Molecular weight |
863.36 Da |
|
Solubility |
Fat-soluble optimized type (nanoemulsion water-soluble formula optional) |
|
Recommended daily dosage |
Health care products：30-200mg/day; Medical aid：100-300mg/day |
|
Storage conditions |
Sealed in a dark place, 2-8°C (activity retention > 3 years) |
Application scenarios and formula guidelines
Dietary supplement development
Heart health capsules: 100mg/capsule + fish oil (Omega-3 synergistic enhancement).
Sports energy tablets: Compounded with PQQ (pyrroloquinoline quinone) to enhance mitochondrial function.
Functional food innovation
Middle-aged and elderly milk powder: 0.1% added amount + calcium, prevent osteoporosis (clinically recommended dose).
Energy drinks: Add 0.5-1g per liter, pH tolerance 3-9 (does not affect flavor).
Medical grade application
Heart failure auxiliary injection: 10mg/mL concentration, combined with standard treatment (physician guidance required).
Anti-cancer auxiliary preparation: Nano-targeted delivery system to reduce chemotherapy side effects.
Usage specifications and contraindications
✅ Recommended solutions
Daily health care: 50-100 mg/day, taken after meals (fat-soluble formulas are recommended to be taken with oils).
Disease support: 200-300 mg/day, taken in 2 doses (doctor monitoring is required).
⛔ Contraindications:
Pregnant women, lactating women and children are prohibited (inadequate safety data).
Use with caution in patients with coagulation disorders (may enhance the efficacy of anticoagulants).
Quality assurance system
• Activity detection: DTNB colorimetric verification is provided for each batch (in compliance with USP standards).
• Stability data: 40°C accelerated for 6 months, purity decreased by <1%.
• Customized services:
Enteric coating tecFlavor modification (masking bitterness, suitable for food addition).
hnology (survival rate in gastric acid environment>90%)
FAQ
Q: What is the difference between fermented coenzyme Q10 and chemically synthesized products?
A: The fermentation process avoids the risk of solvent residues, the purity is ≥98% and contains natural isomers, and the biological activity is increased by 30%.
Q: How to solve the problem of low absorption rate?
A: Using red pine seed oil nanoemulsion technology, the absorption rate is increased from 5% to 60% (pharmacokinetics verification).
Q: Do yousupport pharmaceutical-grade COA documents?
A: Provide DMF filing materials (US DMF# 42135) and cytotoxicity report (MTT method).
Specification Of Analysis
|
Item |
Specification |
|
Maker Compounds |
98% Coenzyme Q10 |
|
Organoleptic |
|
|
Appearance |
Powder |
|
Color |
Yellow |
|
Odor |
Characteristic |
|
Taste |
Characteristic |
|
Physical Characteristics |
|
|
Clarity |
Clear |
|
Particle Size |
100% through 80 mesh |
|
Loss on Drying |
<0.5% |
|
Residue on Ignition |
<0.1% |
|
Heavy metals |
|
|
Total Heavy Metals |
<10ppm |
|
As |
<2.0ppm |
|
Pb |
<2.0ppm |
|
Cd |
<0.5ppm |
|
Hg |
<0.5ppm |
|
Microbiological Tests |
|
|
Total Plate Count |
<1,000cfu/g |
|
Total Yeast & Mold |
<100cfu/g |
|
E. Coli |
Negative |
|
Salmonella |
Negative |
Delivery & Shipping
We accept International Express--Fedex/DHL/UPS, air shipping and sea shipping, We can ship to all over the world, even to some remote areas, such as remote areas of Russia, countries near the north and south poles.
