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The Immunological Function Of Yeast Glucan
Risun Bio-Tech Inc | Updated: May 25, 2017

The Immunological Function of Yeast Glucan 


1. Anti-cancer

The main goal of the current study of anti-cancer function is to strengthen the activity of macrophages in human tissue, dextran is having such a function. (1 → 3) -glucan and its relationship between anti-tumor effect and physicochemical properties were studied. It was found that oral β-glucan was significantly increased by immunohistochemical xenograft tumor model Anti-tumor monoclonal antibody (mAb) in mice to establish the anti-tumor effect.


2. Anti-oxidation, anti-radiation

Β-glucan can effectively remove free radicals in the body, protecting macrophages from radiation and radiation can be free from free radical attacks, so that these macrophages continue to play a normal role. Cell culture experiments show that carboxymethyl β-glucan can inhibit the consumption of antioxidant molecules under ultraviolet radiation and promote the growth of keratin, thus protecting the skin cells. PathchenML and other studies have shown that water-soluble glucan can enhance the rapid recovery of radiation induced by cobalt-60. Treatment of irradiated mice with β-glucan enhances the ability of mice to recover and increases bone marrow viability, increasing the number of white blood cells while increasing the number of spleen cells.


3. Promote wound healing

Because macrophage activity plays an important role in surgery and wound healing, β-glucan has the ability to participate in the body's natural defense and accelerate the healing of skin wounds. Waisun and other studies found that 20 ~ 100mg / ml yeast dextran wipe the animal leg injury, can significantly accelerate the wound healing, the application of 0.1 ~ 0.2mg / kg body weight of the soluble glucan, can reduce the thoracic surgery Of the infection rate.


 4. Lower cholesterol and blood lipids

The special structure of β-glucan can promote the release of lipoprotein and fatty acid, so that the macromolecular lipid in the blood is decomposed into small molecules, which can clarify the blood turbidity caused by excessive blood lipid, and can obviously lower blood cholesterol. Nicolosi et al. Studied 15 obese high-cholesterol men who maintained the same body weight during the study and significantly reduced 8% of total cholesterol in the blood at week 7, based on the 7th week Week decreased by 6%, showing that yeast dextran can significantly reduce plasma cholesterol levels.