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Anti-inflammatory Effects Of Green Soybean Extract Irradisted With Visible Light
Risun Bio-Tech Inc | Updated: Apr 26, 2016


  The light irradiation of food can oxidize several compounds in the food, often resulting in many negative effects on human health. Other compounds, such as vitamin D, are activated by ultraviolet irradiation. Irradiation at visible blue and UV-A wavelengths of green tea leaves caused a larger increase in antioxidant activity than other treatments. We suspected that the light irradiation of some plant extracts might have positive effects on human health. We performed a preliminary investigation of the effects of visible light irradiation on some edible plant extracts. As an index of the effect, we used IL-2 suppression in Jurkat cells (a human T-cell-like cell line), and we confirmed a strong suppressive effect of visible light irradiation to green soybean ethanol extract on IL-2 expression in Jurkat cells.

  Soybean research has indicated that there are various elements in foods made with soybeans that moderate or lessen the development potential for chronic diseases. Examples include the hypocholesterolemic effects of soy phytoestrogen, the cancer risk-reducing properties of the isoflavonoids and the saponins, and the xenobiotic effect of genistein. It appears that there are health benefits to including soybeans in one's diet. Soybeans are commercialized in a wide variety of colors and tones — from yellow to black through green, brown and red. The yellow pigmented soybean is the most abundant and harvested soybean.

  The health benefits of soybeans have been reported to differ according to differences in color. For example, the extracts from black soybeans have a longer low-density lipoprotein oxidation lag time compared to that from yellow soybeans because of the high total polyphenol content in its seed coat. The brown soybean seed coat was shown to have high radical-scavenging activity due to a highly polymerized proanthocyanidin component. Another study showed that a diet enriched in soybean isoflavones and green tea enhanced the immune function of ovariectomized mice (natural killer activity and lymphoproliferation) compared to control mice.

  We recently clarified that water extracts from green soybeans have inhibitory activity for pollinosis with regard to the production of IgE, as well as the ability to regulate B-cell apoptosis, probably by suppressing the expressions of BAFF and APRIL.

  A soybean seed is usually green before it is harvested and becomes yellow during maturation. In the present study, the terms “yellow” and “green” soybean refer to the seed coat cotyledon color of each mature soybean (Glycine max) at post-harvest. We evaluated and compared the effects of green and yellow soybean extracts with or without visible light irradiation on anti-inflammatory activity.