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Yeast β-glucan has a wide range of immune function.
Risun Bio-Tech Inc  Mar 16, 2017

Yeast β-glucan has a Wide Range of Immune Function.


1. Anti-cancer

      The main goal of the current study of anti-cancer function is to strengthen the activity of macrophages in 

human tissue, dextran is having such a function. (1 → 3) -glucan and its relationship between anti-tumor 

effect and physicochemical properties were studied. It was found that oral β-glucan was significantly increased

 by immunohistochemical xenograft tumor model Anti-tumor monoclonal antibody (mAb) in mice to establish 

the anti-tumor effect.


2. Anti-oxidation, anti-radiation

      Β-glucan can effectively remove free radicals in the body, protecting macrophages from radiation and radiation

 can be free from free radical attacks, so that these macrophages continue to play a normal role. Cell culture 

experiments show that carboxymethyl β-glucan can inhibit the consumption of antioxidant molecules under 

ultraviolet radiation and promote the growth of keratin, thus protecting the skin cells. PathchenML and other 

studies have shown that water-soluble glucan can enhance the rapid recovery of radiation induced by 

cobalt-60. Treatment of irradiated mice with β-glucan enhances the ability of mice to recover and increases 

bone marrow viability, increasing the number of white blood cells while increasing the number of spleen cells.


3. Promote wound healing

      Because macrophage activity plays an important role in surgery and wound healing, β-glucan has the ability to

 participate in the body's natural defense and accelerate the healing of skin wounds. Waisun and other studies 

found that 20 ~ 100mg / ml yeast dextran wipe the animal leg injury, can significantly accelerate the wound 

healing, the application of 0.1 ~ 0.2mg / kg body weight of the soluble glucan, can reduce the thoracic surgery

Of the infection rate.


4. Lower cholesterol and blood lipids

      The special structure of β-glucan can promote the release of lipoprotein and fatty acid, so that the 

macromolecular lipid in the blood is decomposed into small molecules, which can clarify the blood turbidity 

caused by excessive blood lipid, which can obviously lower blood cholesterol. Nicolosi et al. Studied 15 obese 

high-cholesterol men who maintained the same body weight during the study and significantly reduced 8% of 

total cholesterol in the blood at week 7, based on the 7th week Week decreased by 6%, showing that yeast 

dextran can significantly reduce plasma cholesterol levels.