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The Function of yeast β-glucan
Risun Bio-Tech Inc  May 23, 2017

The Function of  Yeast β-Glucan


    Yeast is an important food and industrial microorganism with a large amount of beta-1,3 / 1,6-glucan in its cell walls. Yeast β-glucan odorless and odorless, insoluble in water, ethanol, acetone and other organic solvents, with enhanced animal immunity, anti-tumor, anti-infection, anti-virus, lower cholesterol, promote wound healing and other functions, has been Ministry of Health approved as a new resource food, can be added to dairy products, functional drinks, baked goods, candy and other food. Ministry of Health Notice No. 6 of 2012 has extended the use of yeast β-glucan to the larger infant formula milk powder.


    Because yeast β-glucan has not only good enhance immunity and other effects, but also has a fat-like taste, can be used as low-calorie food additives, salad dressing, cheese analogues and other frozen desserts as a substitute for fat, with a wide range The application value.


1. Yeast β-glucan and its function

   Yeast β-glucan is a water-insoluble branched polymer, the main chain to β-1,3 glycosides combined, branched to β-1, 6 glycosides combined, accounting for yeast cell wall dry weight of 30% 35%. Through electron microscopy and other means of analysis, scientists understand the spatial structure of yeast β-glucan, its molecular weight ranging from tens of thousands to several hundred thousand, is a triple spiral form.

1.1 enhance immunity

   By oral yeast β-glucan and other food ingredients are different, they are not stomach and intestinal acid or enzyme hydrolysis directly through the small intestine. The macrophages on the small intestinal mucus cells absorb β-glucan through the beta-glucan receptor, and then activate these cells immediately. Β-1,3-D-glucan by stimulating macrophages [3], a can protect and enhance the immune system play a broad role in the role of white blood cells to play a role in protecting the body from the possible harm to health hazards The Macrophages are a class of major cells involved in nonspecific immunity. It can devour foreign particles and destroy them. Macrophages also give other immune cells such as B cells and T cells to provide signals that move them like infected places. It can also produce growth factors to repair damaged tissue.

1.2 anti-infection, improve disease resistance

   Scientific research shows that yeast β-glucan can significantly increase the efficacy of antibiotics; when used in combination with antibiotics, its stimulation of the role of macrophages can increase the therapeutic effect of drugs. In the β-1,3-D-glucan to enhance the body itself and anti-bacterial ability at the same time, antibiotics can inhibit bacterial aggression, improve the body's resistance. Rat peritonitis experiments confirmed that the use of β-1,3-D-glucan alone had 80% survival (control group survival rate of 20%), the use of antibiotics alone group survival rate of 65 %, While the combined use of both have 10match0% survival rate.

1.3 lower blood lipids

  Β-1,3-D-glucan has the role of absorption of bile acids and bile acid excretion in vitro, and promote cholesterol to bile acid conversion, to maintain the normal metabolism of cholesterol. Nicolos and other 15 obese high cholesterol men were studied. In the study, the patient maintained the same body weight, which significantly reduced the total cholesterol content by 8% in the seventh week and 6% on the seventh week.